An efficient synthesis of indolo[2,3-b]quinoline guanidine derivatives with their in vitro and in vivo study

An optimization of the guanidylation process by verifying the efficacy of common guanylation reagents in order to obtain the guanidine derivatives of indolo[2,3-b]quinoline has been performed. As a result, a high-yield procedure using N,N′-di-Boc-N′′-triflylguanidine was applied to synthesize the gu...

Full description

Saved in:
Bibliographic Details
Published in:Med Chem Res
Main Authors: Sidoryk, Katarzyna, Świtalska, Marta, Rózga, Piotr, Wietrzyk, Joanna, Bujak, Iwona, Żerek, Bartłomiej, Kaczmarek, Łukasz, Cybulski, Marcin
Format: Artigo
Language:Inglês
Published: Springer US 2017
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676820/
https://ncbi.nlm.nih.gov/pubmed/29170613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-017-2028-1
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items