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An efficient synthesis of indolo[2,3-b]quinoline guanidine derivatives with their in vitro and in vivo study
An optimization of the guanidylation process by verifying the efficacy of common guanylation reagents in order to obtain the guanidine derivatives of indolo[2,3-b]quinoline has been performed. As a result, a high-yield procedure using N,N′-di-Boc-N′′-triflylguanidine was applied to synthesize the gu...
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| Опубликовано в: : | Med Chem Res |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Springer US
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5676820/ https://ncbi.nlm.nih.gov/pubmed/29170613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-017-2028-1 |
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