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A novel bicyclic 2,4-diaminopyrimidine inhibitor of Streptococcus suis dihydrofolate reductase

Streptococcus suis is a Gram-positive bacterial pathogen of pigs and an emerging zoonotic pathogen. It has become increasingly resistant to multiple classes of antibiotics. New drug candidates and knowledge of their targets are needed to combat antibiotic-resistant S. suis. In this study, the open-s...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Songsungthong, Warangkhana, Prasopporn, Sunisa, Bohan, Louise, Srimanote, Potjanee, Leartsakulpanich, Ubolsree, Yongkiettrakul, Suganya
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866885/
https://ncbi.nlm.nih.gov/pubmed/33604179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.10743
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