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MiR-34a inhibitor protects mesenchymal stem cells from hyperglycaemic injury through the activation of the SIRT1/FoxO3a autophagy pathway
BACKGROUND: Mesenchymal stem cells (MSCs) are favourable treatments for ischaemic diseases; however, MSCs from diabetic patients are not useful for this purpose. Recent studies have shown that the expression of miR-34a is significantly increased in patients with hyperglycaemia; the precise role of m...
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發表在: | Stem Cell Res Ther |
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Main Authors: | , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
BioMed Central
2021
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7866658/ https://ncbi.nlm.nih.gov/pubmed/33546760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02183-2 |
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