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MiR-34a inhibitor protects mesenchymal stem cells from hyperglycaemic injury through the activation of the SIRT1/FoxO3a autophagy pathway

BACKGROUND: Mesenchymal stem cells (MSCs) are favourable treatments for ischaemic diseases; however, MSCs from diabetic patients are not useful for this purpose. Recent studies have shown that the expression of miR-34a is significantly increased in patients with hyperglycaemia; the precise role of m...

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書目詳細資料
發表在:Stem Cell Res Ther
Main Authors: Zhang, Fengyun, Gao, Fei, Wang, Kun, Liu, Xiaohong, Zhang, Zhuoqi
格式: Artigo
語言:Inglês
出版: BioMed Central 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866658/
https://ncbi.nlm.nih.gov/pubmed/33546760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02183-2
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