miR-181a increases FoxO1 acetylation and promotes granulosa cell apoptosis via SIRT1 downregulation

Oxidative stress impairs follicular development by inducing granulosa cell (GC) apoptosis, which involves enhancement of the transcriptional activity of the pro-apoptotic factor Forkhead box O1 (FoxO1). However, the mechanism by which oxidative stress promotes FoxO1 activity is still unclear. Here,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Dis
Egile Nagusiak: Zhang, Mei, Zhang, Qun, Hu, Yali, Xu, Lu, Jiang, Yue, Zhang, Chunxue, Ding, Lijun, Jiang, Ruiwei, Sun, Jianxin, Sun, Haixiang, Yan, Guijun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680589/
https://ncbi.nlm.nih.gov/pubmed/28981116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.467
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