Cysteine and Folate Metabolism Are Targetable Vulnerabilities of Metastatic Colorectal Cancer

SIMPLE SUMMARY: In this work, we studied the metabolic reprogramming of same-patient-derived cell lines with increasing metastatic potential to develop new therapeutic approaches against metastatic colorectal cancer. Using a novel systems biology approach to integrate multiple layers of omics data,...

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Publicat a:Cancers (Basel)
Autors principals: Tarragó-Celada, Josep, Foguet, Carles, Tarrado-Castellarnau, Míriam, Marin, Silvia, Hernández-Alias, Xavier, Perarnau, Jordi, Morrish, Fionnuala, Hockenbery, David, Gomis, Roger R., Ruppin, Eytan, Yuneva, Mariia, de Atauri, Pedro, Cascante, Marta
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866204/
https://ncbi.nlm.nih.gov/pubmed/33498690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13030425
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