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Human iPSC-Based Modeling of Central Nerve System Disorders for Drug Discovery

A high-throughput drug screen identifies potentially promising therapeutics for clinical trials. However, limitations that persist in current disease modeling with limited physiological relevancy of human patients skew drug responses, hamper translation of clinical efficacy, and contribute to high c...

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書目詳細資料
發表在:Int J Mol Sci
Main Authors: Qian, Lu, TCW, Julia
格式: Artigo
語言:Inglês
出版: MDPI 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865494/
https://ncbi.nlm.nih.gov/pubmed/33530458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031203
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