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Human iPSC-Based Modeling of Central Nerve System Disorders for Drug Discovery

A high-throughput drug screen identifies potentially promising therapeutics for clinical trials. However, limitations that persist in current disease modeling with limited physiological relevancy of human patients skew drug responses, hamper translation of clinical efficacy, and contribute to high c...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Qian, Lu, TCW, Julia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865494/
https://ncbi.nlm.nih.gov/pubmed/33530458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031203
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