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Generation of Human iPSC-derived Neural Progenitor Cells (NPCs) as Drug Discovery Model for Neurological and Mitochondrial Disorders

The high attrition rate in drug development processes calls for additional human-based model systems. However, in the context of brain disorders, sampling live neuronal cells for compound testing is not applicable. The use of human induced pluripotent stem cells (iPSCs) has revolutionized the field...

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Vydáno v:Bio Protoc
Hlavní autoři: Zink, Annika, Lisowski, Pawel, Prigione, Alessandro
Médium: Artigo
Jazyk:Inglês
Vydáno: Bio-Protocol 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008100/
https://ncbi.nlm.nih.gov/pubmed/33796613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3939
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