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Generation of Human iPSC-derived Neural Progenitor Cells (NPCs) as Drug Discovery Model for Neurological and Mitochondrial Disorders

The high attrition rate in drug development processes calls for additional human-based model systems. However, in the context of brain disorders, sampling live neuronal cells for compound testing is not applicable. The use of human induced pluripotent stem cells (iPSCs) has revolutionized the field...

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Detalhes bibliográficos
Publicado no:Bio Protoc
Main Authors: Zink, Annika, Lisowski, Pawel, Prigione, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Bio-Protocol 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008100/
https://ncbi.nlm.nih.gov/pubmed/33796613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3939
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