Bscl2 Deficiency Does Not Directly Impair the Innate Immune Response in a Murine Model of Generalized Lipodystrophy

Congenital Generalized Lipodystrophy type 2 (CGL2) is the most severe form of lipodystrophy and is caused by mutations in the BSCL2 gene. Affected patients exhibit a near complete lack of adipose tissue and suffer severe metabolic disease. A recent study identified infection as a major cause of deat...

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Veröffentlicht in:J Clin Med
Hauptverfasser: Roumane, Ahlima, Mcilroy, George D., Balci, Arda, Han, Weiping, Delibegović, Mirela, Baldassarre, Massimiliano, Newsholme, Philip, Rochford, Justin J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865406/
https://ncbi.nlm.nih.gov/pubmed/33498782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10030441
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