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PROTACs and Building Blocks: The 2D Chemical Space in Very Early Drug Discovery

Targeted protein degradation by PROTACs has emerged as a new modality for the knockdown of a range of proteins, and, more recently, it has become increasingly clear that the PROTAC chemical space requires characterization through a pool of ad hoc physicochemical descriptors. In this study, a new dat...

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Bibliografiska uppgifter
I publikationen:Molecules
Huvudupphovsmän: Ermondi, Giuseppe, Garcia-Jimenez, Diego, Caron, Giulia
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865272/
https://ncbi.nlm.nih.gov/pubmed/33525371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26030672
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