Single-cell atlas of developing murine adrenal gland reveals relation of Schwann cell precursor signature to neuroblastoma phenotype

Neuroblastoma is the most common extracranial solid tumor and accounts for ∼10% of pediatric cancer-related deaths. The exact cell of origin has yet to be elucidated, but it is generally accepted that neuroblastoma derives from the neural crest and should thus be considered an embryonal malignancy....

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Hanemaaijer, Evelyn S., Margaritis, Thanasis, Sanders, Karin, Bos, Frank L., Candelli, Tito, Al-Saati, Hanin, van Noesel, Max M., Meyer-Wentrup, Friederike A. G., van de Wetering, Marc, Holstege, Frank C. P., Clevers, Hans
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2021
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865168/
https://ncbi.nlm.nih.gov/pubmed/33500353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2022350118
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