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Genomic evolution of antibiotic resistance is contingent on genetic background following a long-term experiment with Escherichia coli

Antibiotic resistance is a growing health concern. Efforts to control resistance would benefit from an improved ability to forecast when and how it will evolve. Epistatic interactions between mutations can promote divergent evolutionary trajectories, which complicates our ability to predict evolutio...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Card, Kyle J., Thomas, Misty D., Graves, Joseph L., Barrick, Jeffrey E., Lenski, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865137/
https://ncbi.nlm.nih.gov/pubmed/33441451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2016886118
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