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Genomic evolution of antibiotic resistance is contingent on genetic background following a long-term experiment with Escherichia coli
Antibiotic resistance is a growing health concern. Efforts to control resistance would benefit from an improved ability to forecast when and how it will evolve. Epistatic interactions between mutations can promote divergent evolutionary trajectories, which complicates our ability to predict evolutio...
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| Udgivet i: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7865137/ https://ncbi.nlm.nih.gov/pubmed/33441451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2016886118 |
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