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Structure and binding properties of Pangolin-CoV spike glycoprotein inform the evolution of SARS-CoV-2
Coronaviruses of bats and pangolins have been implicated in the origin and evolution of the pandemic SARS-CoV-2. We show that spikes from Guangdong Pangolin-CoVs, closely related to SARS-CoV-2, bind strongly to human and pangolin ACE2 receptors. We also report the cryo-EM structure of a Pangolin-CoV...
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| Vydáno v: | Nat Commun |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7864994/ https://ncbi.nlm.nih.gov/pubmed/33547281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21006-9 |
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