Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion

Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is initiated by virus binding to the ACE2 cell-surface receptors(1–4), followed by fusion of the virus and cell membranes to release the virus genome into the cell. Both receptor binding and membrane fusion activities are me...

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Veröffentlicht in:Nature
Hauptverfasser: Benton, Donald J., Wrobel, Antoni G., Xu, Pengqi, Roustan, Chloë, Martin, Stephen R., Rosenthal, Peter B., Skehel, John J., Gamblin, Steven J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116727/
https://ncbi.nlm.nih.gov/pubmed/32942285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2772-0
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