The effect of the D614G substitution on the structure of the spike glycoprotein of SARS-CoV-2

The majority of currently circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viruses have mutant spike glycoproteins that contain the D614G substitution. Several studies have suggested that spikes with this substitution are associated with higher virus infectivity. We use cryo-...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Benton, Donald J., Wrobel, Antoni G., Roustan, Chloë, Borg, Annabel, Xu, Pengqi, Martin, Stephen R., Rosenthal, Peter B., Skehel, John J., Gamblin, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7936381/
https://ncbi.nlm.nih.gov/pubmed/33579792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2022586118
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