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Crystal structure of the human PRPK–TPRKB complex
Mutations of the p53-related protein kinase (PRPK) and TP53RK-binding protein (TPRKB) cause Galloway-Mowat syndrome (GAMOS) and are found in various human cancers. We have previously shown that small compounds targeting PRPK showed anti-cancer activity against colon and skin cancer. Here we present...
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| Publicado no: | Commun Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7864929/ https://ncbi.nlm.nih.gov/pubmed/33547416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01683-4 |
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