Targeting PRPK Function Blocks Colon Cancer Metastasis

The biological functions of the p53 related protein kinase (PRPK) remain unclear. We have previously demonstrated that PRPK is phosphorylated by the T-LAK cell-originated protein kinase (TOPK) and that phosphorylated PRPK (p-PRPK) promotes colon cancer metastasis. Here, we analyzed colon adenocarcin...

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Pubblicato in:Mol Cancer Ther
Autori principali: Zykova, Tatyana, Zhu, Feng, Wang, Lei, Li, Haitao, Lim, Do Young, Yao, Ke, Roh, Eunmiri, Yoon, Sang-Pil, Kim, Hong-Gyum, Bae, Ki Beom, Wen, Weihong, Shin, Seung Ho, Nadas, Janos, Li, Yan, Ma, Weiya, Bode, Ann M., Dong, Zigang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940014/
https://ncbi.nlm.nih.gov/pubmed/29483219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-0628
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