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Targeted Deletion of CXCR2 in Myeloid Cells Alters the Tumor Immune Environment to Improve Antitumor Immunity

Recruitment of myeloid-derived suppressor cells (MDSCs) into the tumor microenvironment (TME) contributes to cancer immune evasion. MDSCs express the chemokine receptor CXCR2, and inhibiting CXCR2 suppresses the recruitment of MDSCs into the tumor and the pre-metastatic niche. Here we compared the g...

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Dades bibliogràfiques
Publicat a:Cancer Immunol Res
Autors principals: Yang, Jinming, Yan, Chi, Vilgelm, Anna E., Chen, Sheau-Chiann, Ayers, Gregory D., Johnson, Christopher A., Richmond, Ann
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864868/
https://ncbi.nlm.nih.gov/pubmed/33177110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-20-0312
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