Targeted Deletion of CXCR2 in Myeloid Cells Alters the Tumor Immune Environment to Improve Antitumor Immunity

Recruitment of myeloid-derived suppressor cells (MDSCs) into the tumor microenvironment (TME) contributes to cancer immune evasion. MDSCs express the chemokine receptor CXCR2, and inhibiting CXCR2 suppresses the recruitment of MDSCs into the tumor and the pre-metastatic niche. Here we compared the g...

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Publicado en:Cancer Immunol Res
Autores principales: Yang, Jinming, Yan, Chi, Vilgelm, Anna E., Chen, Sheau-Chiann, Ayers, Gregory D., Johnson, Christopher A., Richmond, Ann
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864868/
https://ncbi.nlm.nih.gov/pubmed/33177110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-20-0312
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