Myeloid IKKβ Promotes Antitumor Immunity by Modulating CCL11 and the Innate Immune Response

Myeloid cells are capable of promoting or eradicating tumor cells and the nodal functions that contribute to their different roles are still obscure. Here, we show that mice with myeloid-specific genetic loss of the NF-κB pathway regulatory kinase IKKβ exhibit more rapid growth of cutaneous and lung...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Yang, Jinming, Hawkins, Oriana E., Barham, Whitney, Gilchuk, Pavlo, Boothby, Mark, Ayers, Gregory D., Joyce, Sebastian, Karin, Michael, Yull, Fiona E., Richmond, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349570/
https://ncbi.nlm.nih.gov/pubmed/25336190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1091
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