Stable transplantation of human mitochondrial DNA by high-throughput, pressurized isolated mitochondrial delivery

Generating mammalian cells with specific mitochondrial DNA (mtDNA)–nuclear DNA (nDNA) combinations is desirable but difficult to achieve and would be enabling for studies of mitochondrial-nuclear communication and coordination in controlling cell fates and functions. We developed ‘MitoPunch’, a pres...

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Dettagli Bibliografici
Pubblicato in:eLife
Autori principali: Sercel, Alexander J, Patananan, Alexander N, Man, Tianxing, Wu, Ting-Hsiang, Yu, Amy K, Guyot, Garret W, Rabizadeh, Shahrooz, Niazi, Kayvan R, Chiou, Pei-Yu, Teitell, Michael A
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2021
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864630/
https://ncbi.nlm.nih.gov/pubmed/33438576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63102
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