Mitochondrial Transfer by Photothermal Nanoblade Restores Metabolite Profile in Mammalian Cells

mtDNA sequence alterations are challenging to generate but desirable for basic studies and potential correction of mtDNA diseases. Here, we report a new method for transferring isolated mitochondria into somatic mammalian cells using a photothermal nanoblade, which bypasses endocytosis and cell fusi...

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Gepubliceerd in:Cell Metab
Hoofdauteurs: Wu, Ting-Hsiang, Sagullo, Enrico, Case, Dana, Zheng, Xin, Li, Yanjing, Hong, Jason S., TeSlaa, Tara, Patananan, Alexander N., McCaffery, J. Michael, Niazi, Kayvan, Braas, Daniel, Koehler, Carla M., Graeber, Thomas G., Chiou, Pei-Yu, Teitell, Michael A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062745/
https://ncbi.nlm.nih.gov/pubmed/27166949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.04.007
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