Mitochondrial Transfer by Photothermal Nanoblade Restores Metabolite Profile in Mammalian Cells

mtDNA sequence alterations are challenging to generate but desirable for basic studies and potential correction of mtDNA diseases. Here, we report a new method for transferring isolated mitochondria into somatic mammalian cells using a photothermal nanoblade, which bypasses endocytosis and cell fusi...

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Bibliografske podrobnosti
izdano v:Cell Metab
Main Authors: Wu, Ting-Hsiang, Sagullo, Enrico, Case, Dana, Zheng, Xin, Li, Yanjing, Hong, Jason S., TeSlaa, Tara, Patananan, Alexander N., McCaffery, J. Michael, Niazi, Kayvan, Braas, Daniel, Koehler, Carla M., Graeber, Thomas G., Chiou, Pei-Yu, Teitell, Michael A.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062745/
https://ncbi.nlm.nih.gov/pubmed/27166949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.04.007
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