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Conformational Landscape of Cytochrome P450 Reductase Interactions

Oxidative reactions catalyzed by Cytochrome P450 enzymes (CYPs), which constitute the most relevant group of drug-metabolizing enzymes, are enabled by their redox partner Cytochrome P450 reductase (CPR). Both proteins are anchored to the membrane of the endoplasmic reticulum and the CPR undergoes a...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Sellner, Manuel, Fischer, André, Don, Charleen G., Smieško, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864194/
https://ncbi.nlm.nih.gov/pubmed/33498551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031023
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