Molecular basis for histone H3 “K4me3-K9me3/2” methylation pattern readout by Spindlin1

Histone recognition by “reader” modules serves as a fundamental mechanism in epigenetic regulation. Previous studies have shown that Spindlin1 is a reader of histone H3K4me3 as well as “K4me3-R8me2a” and promotes transcription of rDNA or Wnt/TCF4 target genes. Here we show that Spindlin1 also acts a...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Zhao, Fan, Liu, Yunan, Su, Xiaonan, Lee, Ji-Eun, Song, Yutong, Wang, Daliang, Ge, Kai, Gao, Juntao, Zhang, Michael Q., Li, Haitao
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2021
Soggetti:
Molecular Biophysics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864079/
https://ncbi.nlm.nih.gov/pubmed/32994220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013649
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi