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Molecular basis for histone H3 “K4me3-K9me3/2” methylation pattern readout by Spindlin1
Histone recognition by “reader” modules serves as a fundamental mechanism in epigenetic regulation. Previous studies have shown that Spindlin1 is a reader of histone H3K4me3 as well as “K4me3-R8me2a” and promotes transcription of rDNA or Wnt/TCF4 target genes. Here we show that Spindlin1 also acts a...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7864079/ https://ncbi.nlm.nih.gov/pubmed/32994220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013649 |
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