Reciprocal activation of HEY1 and NOTCH4 under SOX2 control promotes EMT in head and neck squamous cell carcinoma

Several comprehensive studies have demonstrated that the NOTCH pathway is altered in a bimodal manner in head and neck squamous cell carcinoma (HNSCC). In a previous study, it was found that the NOTCH4/HEY1 pathway was specifically upregulated in HNSCC and promoted epithelial-mesenchymal transition...

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Vydáno v:Int J Oncol
Hlavní autoři: Fukusumi, Takahito, Guo, Theresa W., Ren, Shuling, Haft, Sunny, Liu, Chao, Sakai, Akihiro, Ando, Mizuo, Saito, Yuki, Sadat, Sayed, Califano, Joseph A.
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864008/
https://ncbi.nlm.nih.gov/pubmed/33491747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2020.5156
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