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Iron-mediated degradation of ribosomes under oxidative stress is attenuated by manganese

Protein biosynthesis is fundamental to cellular life and requires the efficient functioning of the translational machinery. At the center of this machinery is the ribosome, a ribonucleoprotein complex that depends heavily on Mg(2+) for structure. Recent work has indicated that other metal cations ca...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Smethurst, Daniel G. J., Kovalev, Nikolay, McKenzie, Erica R., Pestov, Dimitri G., Shcherbik, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863898/
https://ncbi.nlm.nih.gov/pubmed/33040024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015025
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