Cholesterol sensing by CD81 is important for hepatitis C virus entry

CD81 plays a central role in a variety of physiological and pathological processes. Recent structural analysis of CD81 indicates that it contains an intramembrane cholesterol-binding pocket and that interaction with cholesterol may regulate a conformational switch in the large extracellular domain o...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Palor, Machaela, Stejskal, Lenka, Mandal, Piya, Lenman, Annasara, Alberione, María Pía, Kirui, Jared, Moeller, Rebecca, Ebner, Stefan, Meissner, Felix, Gerold, Gisa, Shepherd, Adrian J., Grove, Joe
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2020
Teme:
Microbiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863897/
https://ncbi.nlm.nih.gov/pubmed/32900848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014761
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