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Cholesterol sensing by CD81 is important for hepatitis C virus entry
CD81 plays a central role in a variety of physiological and pathological processes. Recent structural analysis of CD81 indicates that it contains an intramembrane cholesterol-binding pocket and that interaction with cholesterol may regulate a conformational switch in the large extracellular domain o...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7863897/ https://ncbi.nlm.nih.gov/pubmed/32900848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014761 |
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