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Genetic evidence for partial redundancy between the arginine methyltransferases CARM1 and PRMT6

CARM1 is a protein arginine methyltransferase (PRMT) that acts as a coactivator in a number of transcriptional programs. CARM1 orchestrates this coactivator activity in part by depositing the H3R17me2a histone mark in the vicinity of gene promoters that it regulates. However, the gross levels of H3R...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Cheng, Donghang, Gao, Guozhen, Di Lorenzo, Alessandra, Jayne, Sandrine, Hottiger, Michael O., Richard, Stephane, Bedford, Mark T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863876/
https://ncbi.nlm.nih.gov/pubmed/33008887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014704
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