Loss of the major Type I arginine methyltransferase PRMT1 causes substrate scavenging by other PRMTs

Arginine methylation is a common posttranslational modification that is found on both histone and non-histone proteins. Three types of arginine methylation exist in mammalian cells: monomethylarginine (MMA), asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA). PRMT1 is the prima...

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Main Authors: Dhar, Surbhi, Vemulapalli, Vidyasiri, Patananan, Alexander N., Huang, Grace L., Di Lorenzo, Alessandra, Richard, Stephane, Comb, Michael J., Guo, Ailan, Clarke, Steven G., Bedford, Mark T.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575585/
https://ncbi.nlm.nih.gov/pubmed/23419748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01311
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