Functional interactions of adrenodoxin with several human mitochondrial cytochrome P450 enzymes

Seven of the 57 human cytochrome P450 (P450) enzymes are mitochondrial and carry out important reactions with steroids and vitamins A and D. These seven P450s utilize an electron transport chain that includes NADPH, NADPH-adrenodoxin reductase (AdR), and adrenodoxin (Adx) instead of the diflavin NAD...

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Bibliographic Details
Published in:Arch Biochem Biophys
Main Authors: Child, Stella A., Reddish, Michael J., Glass, Sarah M., Goldfarb, Margo H., Barckhausen, Ian R., Guengerich, F. Peter
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863566/
https://ncbi.nlm.nih.gov/pubmed/32980349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2020.108596
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