Testosterone activates glucose metabolism through AMPK and androgen signaling in cardiomyocyte hypertrophy

BACKGROUND: Testosterone regulates nutrient and energy balance to maintain protein synthesis and metabolism in cardiomyocytes, but supraphysiological concentrations induce cardiac hypertrophy. Previously, we determined that testosterone increased glucose uptake—via AMP-activated protein kinase (AMPK...

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Detalhes bibliográficos
Publicado no:Biol Res
Main Authors: Troncoso, Mayarling Francisca, Pavez, Mario, Wilson, Carlos, Lagos, Daniel, Duran, Javier, Ramos, Sebastián, Barrientos, Genaro, Silva, Patricio, Llanos, Paola, Basualto-Alarcón, Carla, Westenbrink, B. Daan, Lavandero, Sergio, Estrada, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863443/
https://ncbi.nlm.nih.gov/pubmed/33546773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40659-021-00328-4
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