Ca(2+)/Calmodulin-Dependent Protein Kinase II and Androgen Signaling Pathways Modulate MEF2 Activity in Testosterone-Induced Cardiac Myocyte Hypertrophy

Testosterone is known to induce cardiac hypertrophy through androgen receptor (AR)-dependent and -independent pathways, but the molecular underpinnings of the androgen action remain poorly understood. Previous work has shown that Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and myocyte-enh...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Duran, Javier, Lagos, Daniel, Pavez, Mario, Troncoso, Mayarling F., Ramos, Sebastián, Barrientos, Genaro, Ibarra, Cristian, Lavandero, Sergio, Estrada, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601904/
https://ncbi.nlm.nih.gov/pubmed/28955223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00604
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