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GDF11 Modulates Ca(2+)-Dependent Smad2/3 Signaling to Prevent Cardiomyocyte Hypertrophy
Growth differentiation factor 11 (GDF11), a member of the transforming growth factor-β family, has been shown to act as a negative regulator in cardiac hypertrophy. Ca(2+) signaling modulates cardiomyocyte growth; however, the role of Ca(2+)-dependent mechanisms in mediating the effects of GDF11 rem...
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| Publié dans: | Int J Mol Sci |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5983757/ https://ncbi.nlm.nih.gov/pubmed/29783655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19051508 |
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