GDF11 Does not Rescue Aging-Related Pathological Hypertrophy

RATIONALE: GDF11 (Growth Differentiation Factor 11) is a member of the transforming growth factor β (TGFβ) super family of secreted factors. A recent study showed that reduced GDF11 blood levels with aging was associated with pathological cardiac hypertrophy (PCH), and restoring GDF11 to normal leve...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Smith, Shavonn C., Zhang, Xiaoxiao, Zhang, Xiaoying, Gross, Polina, Starosta, Timothy, Mohsin, Sadia, Franti, Michael, Gupta, Priyanka, Hayes, David, Myzithras, Maria, Kahn, Julius, Tanner, James, Weldon, Steven M., Khalil, Ashraf, Guo, Xinji, Sabri, Abdelkarim, Chen, Xiongwen, MacDonnell, Scott, Houser, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636963/
https://ncbi.nlm.nih.gov/pubmed/26383970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.307527
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