Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model

Hypertrophic cardiomyopathy (HCM) is one of the most common genetic cardiac diseases and among the leading causes of sudden cardiac death (SCD) in the young. The cellular mechanisms leading to SCD in HCM are not well known. Prolongation of the action potential (AP) duration (APD) is a common feature...

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Vydáno v:Am J Physiol Heart Circ Physiol
Hlavní autoři: Toib, Amir, Zhang, Chen, Borghetti, Giulia, Zhang, Xiaoxiao, Wallner, Markus, Yang, Yijun, Troupes, Constantine D., Kubo, Hajime, Sharp, Thomas E., Feldsott, Eric, Berretta, Remus M., Zalavadia, Neil, Trappanese, Danielle M., Harper, Shavonn, Gross, Polina, Chen, Xiongwen, Mohsin, Sadia, Houser, Steven R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625176/
https://ncbi.nlm.nih.gov/pubmed/28646025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00167.2017
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