Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model

Hypertrophic cardiomyopathy (HCM) is one of the most common genetic cardiac diseases and among the leading causes of sudden cardiac death (SCD) in the young. The cellular mechanisms leading to SCD in HCM are not well known. Prolongation of the action potential (AP) duration (APD) is a common feature...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Toib, Amir, Zhang, Chen, Borghetti, Giulia, Zhang, Xiaoxiao, Wallner, Markus, Yang, Yijun, Troupes, Constantine D., Kubo, Hajime, Sharp, Thomas E., Feldsott, Eric, Berretta, Remus M., Zalavadia, Neil, Trappanese, Danielle M., Harper, Shavonn, Gross, Polina, Chen, Xiongwen, Mohsin, Sadia, Houser, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625176/
https://ncbi.nlm.nih.gov/pubmed/28646025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00167.2017
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