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Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model

Hypertrophic cardiomyopathy (HCM) is one of the most common genetic cardiac diseases and among the leading causes of sudden cardiac death (SCD) in the young. The cellular mechanisms leading to SCD in HCM are not well known. Prolongation of the action potential (AP) duration (APD) is a common feature...

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Détails bibliographiques
Publié dans:Am J Physiol Heart Circ Physiol
Auteurs principaux: Toib, Amir, Zhang, Chen, Borghetti, Giulia, Zhang, Xiaoxiao, Wallner, Markus, Yang, Yijun, Troupes, Constantine D., Kubo, Hajime, Sharp, Thomas E., Feldsott, Eric, Berretta, Remus M., Zalavadia, Neil, Trappanese, Danielle M., Harper, Shavonn, Gross, Polina, Chen, Xiongwen, Mohsin, Sadia, Houser, Steven R.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625176/
https://ncbi.nlm.nih.gov/pubmed/28646025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00167.2017
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