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β(1)-Adrenergic receptor activation induces mouse cardiac myocyte death through both L-type calcium channel-dependent and -independent pathways

Cardiac diseases persistently increase the contractility demands of cardiac myocytes, which require activation of the sympathetic nervous system and subsequent increases in myocyte Ca(2+) transients. Persistent exposure to sympathetic and/or Ca(2+) stress is associated with myocyte death. This study...

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Библиографические подробности
Главные авторы: Wang, Wei, Zhang, Hongyu, Gao, Hui, Kubo, Hajime, Berretta, Remus M., Chen, Xiongwen, Houser, Steven R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930381/
https://ncbi.nlm.nih.gov/pubmed/20495143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00392.2010
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