Protein disulfide isomerase ERp57 protects early muscle denervation in experimental ALS

Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disease that affects motoneurons. Mutations in superoxide dismutase 1 (SOD1) have been described as a causative genetic factor for ALS. Mice overexpressing ALS-linked mutant SOD1 develop ALS symptoms accompanied by histopat...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Rozas, Pablo, Pinto, Cristina, Martínez Traub, Francisca, Díaz, Rodrigo, Pérez, Viviana, Becerra, Daniela, Ojeda, Patricia, Ojeda, Jorge, Wright, Madison T., Mella, Jessica, Plate, Lars, Henríquez, Juan Pablo, Hetz, Claudio, Medinas, Danilo B.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863244/
https://ncbi.nlm.nih.gov/pubmed/33541434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01116-z
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