The nuclear import of the transcription factor MyoD is reduced in mesenchymal stem cells grown in a 3D micro-engineered niche

Smart biomaterials are increasingly being used to control stem cell fate in vitro by the recapitulation of the native niche microenvironment. By integrating experimental measurements with numerical models, we show that in mesenchymal stem cells grown inside a 3D synthetic niche both nuclear transpor...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Jacchetti, Emanuela, Nasehi, Ramin, Boeri, Lucia, Parodi, Valentina, Negro, Alessandro, Albani, Diego, Osellame, Roberto, Cerullo, Giulio, Matas, Jose Felix Rodriguez, Raimondi, Manuela Teresa
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862644/
https://ncbi.nlm.nih.gov/pubmed/33542304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81920-2
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