The nuclear import of the transcription factor MyoD is reduced in mesenchymal stem cells grown in a 3D micro-engineered niche

Smart biomaterials are increasingly being used to control stem cell fate in vitro by the recapitulation of the native niche microenvironment. By integrating experimental measurements with numerical models, we show that in mesenchymal stem cells grown inside a 3D synthetic niche both nuclear transpor...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jacchetti, Emanuela, Nasehi, Ramin, Boeri, Lucia, Parodi, Valentina, Negro, Alessandro, Albani, Diego, Osellame, Roberto, Cerullo, Giulio, Matas, Jose Felix Rodriguez, Raimondi, Manuela Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862644/
https://ncbi.nlm.nih.gov/pubmed/33542304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81920-2
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