The nuclear import of the transcription factor MyoD is reduced in mesenchymal stem cells grown in a 3D micro-engineered niche

Smart biomaterials are increasingly being used to control stem cell fate in vitro by the recapitulation of the native niche microenvironment. By integrating experimental measurements with numerical models, we show that in mesenchymal stem cells grown inside a 3D synthetic niche both nuclear transpor...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Jacchetti, Emanuela, Nasehi, Ramin, Boeri, Lucia, Parodi, Valentina, Negro, Alessandro, Albani, Diego, Osellame, Roberto, Cerullo, Giulio, Matas, Jose Felix Rodriguez, Raimondi, Manuela Teresa
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2021
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862644/
https://ncbi.nlm.nih.gov/pubmed/33542304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81920-2
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