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Polygonogram with isobolographic synergy for three-drug combinations of phenobarbital with second-generation antiepileptic drugs in the tonic–clonic seizure model in mice

BACKGROUND: Combination therapy consisting of two or more antiepileptic drugs (AEDs) is usually prescribed for patients with refractory epilepsy. The drug–drug interactions, which may occur among currently available AEDs, are the principal criterion taken by physicians when prescribing the AED combi...

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Detalhes bibliográficos
Publicado no:Pharmacol Rep
Main Authors: Łuszczki, Jarogniew J., Podgórska, Dominika, Kozińska, Justyna, Jankiewicz, Marek, Plewa, Zbigniew, Kominek, Mateusz, Żółkowska, Dorota, Florek-Łuszczki, Magdalena
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862539/
https://ncbi.nlm.nih.gov/pubmed/33025394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s43440-020-00164-5
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