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Polygonogram and isobolographic analysis of interactions between various novel antiepileptic drugs in the 6-Hz corneal stimulation-induced seizure model in mice

Pharmacotherapy with two antiepileptic drugs in combination is usually prescribed to epilepsy patients with refractory seizures. The choice of antiepileptic drugs in combination should be based on synergistic cooperation of the drugs with respect to suppression of seizures. The selection of synergis...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Luszczki, Jarogniew J., Panasiuk, Anna, Zagaja, Mirosław, Karwan, Sławomir, Bojar, Hubert, Plewa, Zbigniew, Florek-Łuszczki, Magdalena
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263629/
https://ncbi.nlm.nih.gov/pubmed/32479532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234070
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