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TonEBP regulates the hyperosmotic expression of aquaporin 1 and 5 in the intervertebral disc
The central region of the intervertebral disc (IVD) is rich in proteoglycans, leading to a hyperosmotic environment, which fluctuates with daily loading. The cells of the nucleus pulposus (NP cells) have adapted to this environment via the function of tonicity enhancer binding protein (TonEBP), and...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7862284/ https://ncbi.nlm.nih.gov/pubmed/33542263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81838-9 |
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