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Population Pharmacokinetics of Brigatinib in Healthy Volunteers and Patients With Cancer

BACKGROUND AND OBJECTIVES: Brigatinib is an oral tyrosine kinase inhibitor approved in multiple countries for the treatment of patients with anaplastic lymphoma kinase-positive metastatic non-small cell lung cancer who have progressed on or are intolerant to crizotinib. We report a population pharma...

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Опубликовано в: :Clin Pharmacokinet
Главные авторы: Gupta, Neeraj, Wang, Xiaohui, Offman, Elliot, Prohn, Marita, Narasimhan, Narayana, Kerstein, David, Hanley, Michael J., Venkatakrishnan, Karthik
Формат: Artigo
Язык:Inglês
Опубликовано: Springer International Publishing 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862202/
https://ncbi.nlm.nih.gov/pubmed/32816246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-020-00929-4
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