Aryl Hydrocarbon Receptor Activation in Astrocytes by Laquinimod Ameliorates Autoimmune Inflammation in the CNS

OBJECTIVE: MS is an autoimmune demyelinating disease of the CNS, which causes neurologic deficits in young adults and leads to progressive disability. The aryl hydrocarbon receptor (AHR), a ligand-activated transcription factor, can drive anti-inflammatory functions in peripheral immune cells and al...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Neurol Neuroimmunol Neuroinflamm
Hlavní autoři: Rothhammer, Veit, Kenison, Jessica E., Li, Zahorong, Tjon, Emily, Takenaka, Maisa C., Chao, Chun-Cheih, Alves de Lima, Kalil, Borucki, Davis M., Kaye, Joel, Quintana, Francisco J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2021
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862099/
https://ncbi.nlm.nih.gov/pubmed/33408169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000946
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky