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Apigenin Alleviates Liver Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Autophagy via TGF-β1/Smad3 and p38/PPARα Pathways
OBJECTIVE: The aim of this study is to confirm the hepatocellular protective functions of apigenin and the molecular mechanism on liver fibrosis in mice. METHODS: Carbon tetrachloride (CCl(4)) and bile duct ligature (BDL) mouse fibrosis models were used to investigate the effects of apigenin on live...
Kaydedildi:
| Yayımlandı: | PPAR Res |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Hindawi
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7861947/ https://ncbi.nlm.nih.gov/pubmed/33574836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6651839 |
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